DL650-E3 Aptamer Details
ID# 7990
Structure
Chemistry
RNA
Target
PC-3
Category
Cells
Affinity (Kd)
146 nM
Length
36
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-rGprGprCprUprUprUprCprGprGprGprCprUprUprUprCprGprGprCprAprAprCprAprUprCprAprGprCprCprCprCprUprCprAprGprCprCp-3'
Molecular Weight:
Extinction Coefficient:
Binding Conditions / Buffer
DPBS with Ca2+ and Mg2+ (ThermoFisher, Waltham, MA)
Binding Temp: 37°C
Refolding Protocol
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Powell Gray B, Kelly L, Ahrens DP et al. Tunable cytotoxic aptamer-drug conjugates for the treatment of prostate cancer. Proc. Natl. Acad. Sci. U.S.A. doi: 10.1073/pnas.1717705115 (2018)
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