CoV2-RBD-4C Aptamer Details
ID# 8161
Structure
Chemistry
DNA
Target
SARS-CoV-2 S protein / SARS-CoV-2 RBD
Category
Protein
Affinity (Kd)
13.6 nM
Length
276
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-dApdTpdCpdCpdApdGpdApdGpdTpdGpdApdCpdGpdCpdApdGpdCpdApdTpdTpdTpdCpdApdTpdCpdGpdGpdGpdTpdCpdCpdApdApdApdApdGpdGpdGpdGpdCpdTpdGpdCpdTpdCpdGpdGpdGpdApdTpdTpdGpdCpdGpdGpdApdTpdApdTpdGpdGpdApdCpdApdCpdGpdTp-3'
Molecular Weight:
Extinction Coefficient:
Binding Conditions / Buffer
Buffer, Binding - PBS with 0.55 mM MgCl2
Binding Temp: Annealed at 95 °C, after which it was immediately cooled onice for 5 min and then at 25 °C for 10 min.
Refolding Protocol
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Song, Y., Song, J., Wei, X., Huang, M., Sun, M., Zhu, L., Lin, B., Shen, H., Zhu, Z., and C. Yang. 2020. Discovery of Aptamers Targeting the Receptor-Binding Domain of the SARS-CoV‑2 Spike Glycoprotein. Analytical Chemistry 2020, 92, 9895−9900. https://dx.doi.org/10.1021/acs.analchem.0c01394
Request a Quote
Have your aptamer oligo synthesized by Aptagen.