CoV2-6C3 Aptamer Details
ID# 8195
Structure
Chemistry
DNA
Target
SARS-CoV-2 Spike Protein RBD
Category
Protein
Affinity (Kd)
44.78 nM
Length
46
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-dCpdGpdCpdApdGpdCpdApdCpdCpdCpdApdApdGpdApdApdCpdApdApdGpdGpdApdCpdTpdGpdCpdTpdTpdApdGpdGpdApdTpdTpdGpdCpdGpdApdTpdApdGpdGpdTpdTpdCpdGpdGp-3'
Molecular Weight:
Extinction Coefficient:
Binding Conditions / Buffer
1X PBS, pH=7.4, including 136.8 mM NaCl, 10.1 mM Na2HPO4, 2.7 mM KCl, 1.8 mM KH2PO4, 0.55 mM MgCl2
Binding Temp: 25°C
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Sun, M., Liu, S., Wei, X., Wan, S., Huang, M., Song, T., Lu, Y., Weng, X., Lin, Z., Chen, H., Song, Y., & Yang, C. (2021). Aptamer Blocking Strategy Inhibits SARS-CoV-2 Virus Infection. Angewandte Chemie (International ed. in English), 60(18), 10266–10272. https://doi.org/10.1002/anie.202100225
Request a Quote
Have your aptamer oligo synthesized by Aptagen.
