Aptagen

Collagen XIa116mer (D1) Aptamer Details

ID# 10107
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Structure
Collagen XIa116mer (D1) structure
Chemistry
DNA
Target
16-amino acid peptide from collagen XIa1
Category
Peptide
Affinity (Kd)
25 nM
Length
40
Aptazyme
No

Sequence (3-char table code)

G A C U/T
5'-dGpdGpdTpdTpdGpdApdCpdGpdGpdCpdApdGpdTpdCpdGpdGpdCpdGpdGpdTpdApdTpdGpdCpdGpdCpdApdTpdApdTpdCpdGpdTpdGpdTpdTpdGpdGpdTpdAp-3'
Molecular Weight: 2455.1 g/mole
Extinction Coefficient: 385800

Binding Conditions / Buffer

For 1 hour at 37 C, template was incubated with 1X PBS, 1 μg/ml of BSA (bovine-serum albumin), and 2.34 μg/ml of tRNA
Binding Temp: 37°C

Refolding Protocol

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Ramón Lorenzo-Gómez, Rebeca Miranda-Castro, Juan R. de los Toyos, Noemí de-los-Santos-Álvarez, María Jesús Lobo-Castañón, Aptamers targeting a tumor-associated extracellular matrix component: The human mature collagen XIα1, Analytica Chimica Acta, Volume 1189, 2022, 339206, ISSN 0003-2670, https://doi.org/10.1016/j.aca.2021.339206.
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