Cocaine Aptamer Aptamer Details
ID# 7966
Structure
Chemistry
DNA
Target
Cocaine
Category
Small Organic
Affinity (Kd)
N/A nM
Length
43
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-dGpdApdCpdApdApdGpdGpdApdTpdApdApdApdTpdCpdCpdTpdTpdCpdApdApdTpdGpdApdApdGpdTpdGpdGpdGpdTpdCpdApdCpdTpdCpdApdTpdCpdTpdGpdTpdGpdAp-3'
Molecular Weight: 13274.72
Extinction Coefficient: 429800
Binding Conditions / Buffer
The buffer for immobilization of ssDNA probe consisted of 0.8M phosphate buffer (PB) with 1.0M NaCl, 5 mM MgCl2 and 1 mM ethylenediamine tetraacetic acid (EDTA), pH 7.0. The DNA hybridization buffer and cocaine incubation buffer was composed of 50mM PB with 100mM K2SO4 (pH 7.4).
Binding Temp: 25°C
Refolding Protocol
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Yang, Z. et al. Community Sewage Sensors towards Evaluation of Drug Use Trends: Detection of Cocaine in Wastewater with DNA-Directed Immobilization Aptamer Sensors. Sci. Rep. 6, 21024; doi: 10.1038/srep21024 (2016).
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