CN-ES2 (17β-Estradiol) Aptamer Details

ID# 9655

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Structure

Chemistry

DNA

Target

17β-Estradiol

Sequence (3-char table code)

G A C U/T

dCpdGpdApdCpdTpdTpdApdApdGpdGpdTpdApdTpdGpdTpdGpdApdTpdCpdTpdTpdApdGpdTpdTpdGpdTpdApdGpdTpdTpdCpdApdApdGpdTpdCpdGp

Molecular Weight: 11753.7 g/mole

Extinction Coefficient: 374100

Binding Conditions / Buffer

SELEX Buffer: 20 mM Tris, pH 7.4, 500 mM NaCl, 10 mM MgCl2. Sensing Buffer: 20 mM HEPES, pH 7.4, 100 mM NaCl, 10 mM MgCl2

Binding Temp: Room Temperature°C

Refolding Protocol

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Capture-SELEX of DNA Aptamers for Estradiol Specifically and Estrogenic Compounds Collectively Chenqi Niu, Chong Zhang, and Juewen Liu Environmental Science & Technology 2022 56 (24), 17702-17711 DOI: 10.1021/acs.est.2c05808

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