Aptagen

Chlorpromazine (CHL-3) Aptamer Details

ID# 10031
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Structure
Chlorpromazine (CHL-3) structure
Chemistry
DNA
Target
chlorpromazine
Category
Other
Affinity (Kd)
69.8 ± 9.81 nM
Length
55
Aptazyme
No

Sequence (3-char table code)

G A C U/T
5'-dTpdCpdGpdGpdApdGpdGpdGpdApdApdGpdTpdGpdCpdApdCpdCpdCpdApdTpdTpdCpdTpdTpdGpdGpdApdApdApdCpdApdGpdGpdApdGpdCpdTpdCpdCpdTpdGpdApdApdCpdCpdGpdCpdCpdCpdApdCpdApdCpdGpdCp-3'
Molecular Weight: 16900 g/mole
Extinction Coefficient: 520400

Binding Conditions / Buffer

50 mM Tris-HCl, 5 mM KCl, 100 mM NaCl, 1 mM MgCl2, pH 7.4
Binding Temp: 37°C

Refolding Protocol

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Mingqian Song, Changxin Li, Shijia Wu, Nuo Duan, Screening of specific aptamers against chlorpromazine and construction of novel ratiometric fluorescent aptasensor based on metal-organic framework, Talanta, Volume 252, 2023, 123850, ISSN 0039-9140, https://doi.org/10.1016/j.talanta.2022.123850.
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