Celiac disease Aptamer (Gli4) Aptamer Details

ID# 7895

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Structure

Chemistry

DNA

Target

33-mer (immunodominant peptide from alpha2-gliadin)

Sequence (3-char table code)

G A C U/T

dCpdCpdApdGpdTpdCpdTpdCpdCpdCpdGpdTpdTpdTpdApdCpdCpdGpdCpdGpdCpdCpdTpdApdCpdApdCpdApdTpdGpdTpdCpdTpdGpdApdApdTpdGpdCpdCp

Molecular Weight: 12103.86

Extinction Coefficient: 357500

Binding Conditions / Buffer

50 mM TRIS-HCl, 0.25 M NaCl, 5mM MgCl2

Binding Temp:

Refolding Protocol

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Gonzalez, S, et. al. "Aptamer Binding to Celiac Disease-Triggering Hydrophobic Proteins A Sensitive Gluten Detection Approach." 2014. Analytical Chemistry 86: 2733-39.

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