CD59 (sp22) Aptamer Details
ID# 7746
Structure
Chemistry
Peptide
Target
CD59
Category
Protein
Affinity (Kd)
N/A nM
Length
22
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-AlaCysHisTrpProTrpCysHisGlyTrpHisSerAlaCysAspLeuProMetHisProMetCys-3'
Molecular Weight: 2922.43
Extinction Coefficient:
Binding Conditions / Buffer
Washed with cold PBS and glycine buffer added. Chilled on ice for 15 minutes.
Binding Temp:
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Li et al. "Identification of a novel short peptide seal specific to CD59 and its effect on HeLa cell growth and apoptosis." Cell Oncol. 35:355-365.
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