CD38jd4a Aptamer against CD38 in Multiple Myeloma Aptamer Details

ID# 9402

Structure

Chemistry

DNA

Target

CD38, a transmembrane glycoprotein that is expressed on the surface of plasma cells and a therapeutic target for Multiple Myeloma

Sequence (3-char table code)

G A C U/T

5'-dTpdCpdCpdApdCpdApdGpdTpdGpdGpdCpdTpdApdGpdGpdTpdGpdTpdCpdTpdCpdCpdTpdTpdCpdGpdApdCpdTpdApdCpdGpdGpdGpdTpdTpdGpdGpdGpdTpdTpdGpdGpdGpdTpdTpdApdGpdGpdGpdTpdGpdTpdGpdTpdCpdGpdTpdCpdGp-3'

Molecular Weight: 18639 g/mole

Extinction Coefficient: 559600

Binding Conditions / Buffer

DPBS (5 mmol/L MgCl2 and 4.5 g/L glucose) alongside 1 mg/mL BSA (bovine serum albumin) and 0.1 mg/mL HS-DNA (Herring sperm DNA).

Binding Temp: 25 °C °C

Refolding Protocol

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Di Jiang, Ling Wang, Hengyi Lin, Xiaoqiu Wu, Mingxin Zhang, Songxiao Xu, Zhenhao Long, Tao Bing, Selection and characterization of aptamers against CD38 for clinical diagnostics, Chinese Chemical Letters (2025), Doi: https://doi.org/10.1016/j.cclet.2025.111502

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