??-Catenin Aptamer Details

ID# 7833

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Structure

Chemistry

RNA

Target

Arm 1-12 of B-catenin

Sequence (3-char table code)

G A C U/T

5'-rGprGprAp rCprGprCp rGprUprGp rGprUprAp rCprCprAp rGprGprCp rCprGprAp rUprCprUp rAprUprGp rGprAprCp rGprCprUp rAprUprAp rGprGprCp rAprCprAp rCprCprGp rGprAprUp rAprCprUp rUprUprAp rAprCprGp rAprUprUp rGprGprCp rUprAprAp rGprCprUp rUprCprCp rGprCprGp rGprGprGp rAprUprCp-3'

Molecular Weight: 26107.74

Extinction Coefficient: 792100

Binding Conditions / Buffer

Binding buffer: 25 mM HEPES (pH 7.5), 150 mM NaCl, 1 mM MgCl2, 2 mM DTT, and 40 U RNase inhibitor.

Binding Temp:

Refolding Protocol

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Lee HK, Choi YS, Park YA, et al. (2006) Modulation of oncogenic transcription and alternative splicing by beta-catenin and an RNA aptamer in colon cancer cells.

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