Botulinum neurotoxin type A (BoNT A) Aptamer (S132B-C22) Aptamer Details

ID# 7888

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Structure

Chemistry

DNA

Target

BoNT A Light Chain

Sequence (3-char table code)

G A C U/T

dGpdGpdGpdApdGpdGpdApdGpdGpdApdGpdApdGpdApdTpdGpdTpdGpdApdApdCpdTpdTpdGpdApdCpdApdGpdCpdGpdTpdGpdCpdCpdTpdApdGpdApdApdGpdTpdCpdCpdApdApdGpdCpdTpdTpdApdApdApdTpdApdApdCpdCpdApdCpdGpdCpdTpdCpdGpdApdCpdApdApdGpdCpdApdGpdApdApdApdCpdTpdCpdTpdApdCpdApdCpdTpdGpdGpdApdCpdTpdGpdGpdCpdGp

Molecular Weight: 28858.79

Extinction Coefficient: 924400

Binding Conditions / Buffer

PBS pH 7.4, 300 mM NaCl, 3mM MgCl2, 5mM DTT, 1mg/ml BSA, 0.2 % Tween, 1mg/ml heparin

Binding Temp: 25°C

Refolding Protocol

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Chang, T., Blank, M., Janardhanan, P., Singh, B., Mello, C., Blind, M., Cai, S. "In vitro selection of RNA aptamers that inhibit the activity of type A botulinum neurotoxin." Biochemical and Biophysical Research Communications 396(2010): 854-860.

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