Aptagen

B23 LH aptamer Aptamer Details

ID# 7995
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Structure
B23 LH aptamer structure
Chemistry
DNA
Target
luteinising hormone
Category
Protein
Affinity (Kd)
321 nM
Length
35
Aptazyme
No

Sequence (3-char table code)

G A C U/T
5'-dTpdApdTpdGpdGpdTpdApdTpdGpdCpdTpdGpdTpdGpdTpdGpdGpdTpdApdTpdGpdGpdGpdGpdTpdGpdGpdCpdGpdTpdGpdCpdTpdCpdTp-3'
Molecular Weight:
Extinction Coefficient:

Binding Conditions / Buffer

PBS
Binding Temp: 25°C

Refolding Protocol

If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Liang S, Kinghorn AB, Voliotis M, et al. Measuring luteinising hormone pulsatility with a robotic aptamer-enabled electrochemical reader. Nat Commun. 2019;10(1):852. Published 2019 Feb 20. doi:10.1038/s41467-019-08799-6
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