AptD2 Aptamer Details
ID# 8163
Structure
Chemistry
DNA
Target
DEN-NS1
Category
Protein
Affinity (Kd)
104 nM
Length
63
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5′-dGpdGpdCpdTpdGpdGpdTpdCpdCpdGpDspdCpdTpdGpdGpdGpdApdApdCpdApdApdGpDspdGpdGpdCpdGpdGpdGpdApdGpdGpdGpdApPapdGpdGpdGpdTpdGpdTpdGpdGpdGpdTpdGpdCpdGpdApdCpdApdApdGpdCpdGpdGpdApdCpdCpdApdGpdCpdCp-3′
Molecular Weight:
Extinction Coefficient:
Binding Conditions / Buffer
23°C
Binding Temp: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Ken-ichiro Matsunaga, Michiko Kimoto, Vanessa Weixun Lim, Hui Pen Tan, Yu Qian Wong, William Sun, Shawn Vasoo, Yee Sin Leo, Ichiro Hirao, High-affinity five/six-letter DNA aptamers with superior specificity enabling the detection of dengue NS1 protein variants beyond the serotype identification, Nucleic Acids Research, 2021;, gkab515, https://doi.org/10.1093/nar/gkab515
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