Aptamer MN711 against Neurofilament Light Chain (NfL) – Alzheimer’s disease Aptamer Details

ID# 9940

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Structure

Chemistry

DNA

Target

Neurofilament Light Chain (NfL) - Alzheimer's disease

Sequence (3-char table code)

G A C U/T

5'-dGpdGpdTpdGpdGpdTpdGpdTpdGpdGpdTpdGpdGpdGpdTpdGpdGpdGpdTpdTpdGpdTpdCpdTpdGpdTpdGpdTpdGpdGp-3'

Molecular Weight: 9499.1 g/mole

Extinction Coefficient: 284

Binding Conditions / Buffer

Binding activity was detected separately in both 1X PBS and donor human plasma.

Binding Temp: 25°C

Refolding Protocol

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Matsumoto, M., Ikebukuro, K., Tsukakoshi, K., 2026. Competitive-selex discovery of DNA aptamers selective for neurofilament light chain in human plasma. Biochemical and Biophysical Research Communications 796, 153151. doi:10.1016/j.bbrc.2025.153151

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