Aptagen

Aptamer MA Aptamer Details

ID# 8176
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Structure
Aptamer MA structure
Chemistry
DNA
Target
methylenedioxypyrovalerone (MDPV)
Category
Small Organic
Affinity (Kd)
7 nM
Length
46
Aptazyme
No

Sequence (3-char table code)

G A C U/T
5'-dCpdTpdTpdApdCpdGpdApdCpdTpdCpdApdGpdGpdCpdApdTpdTpdTpdTpdGpdCpdCpdGpdGpdGpdTpdApdApdCpdGpdApdApdGpdTpdTpdApdCpdTpdGpdTpdCpdGpdTpdApdApdGp-3'
Molecular Weight: 14134.82
Extinction Coefficient: 441918

Binding Conditions / Buffer

10 mM Tris–HCl, 0.5 mM MgCl2, 20 mM NaCl, pH 7.4
Binding Temp: 23°C

Refolding Protocol

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Haixiang Yu, Weijuan Yang, Obtin Alkhamis, Juan Canoura, Kyung-Ae Yang, Yi Xiao, In vitro isolation of small-molecule-binding aptamers with intrinsic dye-displacement functionality, Nucleic Acids Research, Volume 46, Issue 8, 4 May 2018, Page e43, https://doi.org/10.1093/nar/gky026
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