Aptamer ILU-01107c against Creatine kinase-MM (CK-MM) Aptamer Details

ID# 9559

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Structure

Chemistry

DNA

Target

Creatine kinase-MM (CK-MM)

Sequence (3-char table code)

G A C U/T

5'-dTpdApdGpdApdCpdCpdTpdGpdCpdApdTpdTpdTpdCpdTpdGpdCpdApdGpdCpdGpdApdTpdTpdCpdTpdTpdGpdTpdTpdTpdTpdGpdCpdApdApdApdApdApdTpdGpdCpdApdGpdCpdTpdTpdCpdTpdApdAp-3'

Molecular Weight: 15629.2 g/mole

Extinction Coefficient: 478200

Binding Conditions / Buffer

1X SELEX Buffer: 100 mM HEPES, 150 mM NaCl, 190 mM KCl, 20 mM CaCl2, and 2.5 mM MgCl2

Binding Temp: 25°C

Refolding Protocol

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Liao, A. M., Agrawal, S., Benson, J. C., & Caltagirone, G. T. (2024). Selection of aptamer for creatine Kinase-MM as a marker for muscular dystrophy and myocardial infarction. Current Research in Biotechnology, 7, 100229. https://doi.org/10.1016/j.crbiot.2024.100229.

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