Aptamer Glu3 against Glucosepane Aptamer Details
ID# 9647
Structure
Chemistry
DNA
Target
Glucosepane
Category
Protein
Affinity (Kd)
17.10 nM
Length
86
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-dTpdApdGpdGpdGpdApdApdGpdApdGpdApdApdGpdGpdApdCpdApdTpdApdTpdGpdApdTpdGpdCpdGpdCpdGpdCpdApdGpdApdTpdTpdApdApdCpdCpdCpdCpdCpdCpdApdApdTpdGpdCpdTpdGpdCpdApdCpdCpdGpdApdGpdCpdCpdApdCpdGpdApdTpdTpdTpdGpdApdCpdTpdApdGpdTpdApdCpdApdTpdGpdApdCpdCpdApdCpdTpdTpdGpdAp-3'
Molecular Weight: 26537.2 g/mole
Extinction Coefficient: 846200
Binding Conditions / Buffer
(100 mM NaCl, 20 mM Tris-HCl, 2 mM MgCl2, 5 mM KCl, 1 mM CaCl2, 0.02% (v/v) Tween 20, pH 7.6)
Binding Temp: 25°C
Refolding Protocol
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Li, Runliu & Draphoen, Bastian & Lindén, Mika & Singh, Karmveer & scharffetter-kochanek, Karin & Stürmer, Andreas & Rosenau, Frank & Kissmann, Ann-Kathrin. (2025). FluMag-SELEX derived specific individual aptamers can fluorescently label the ageing immanent protein-crosslinker glucosepane in diabetic mouse tissues. Nanoscale horizons. 10. 10.1039/d5nh00263j.
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