Aptamer Apt-4 against TIMP-1 Protein Aptamer Details

ID# 9399

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Structure

Chemistry

DNA

Target

Tissue inhibitor of metalloproteinases 1

Sequence (3-char table code)

G A C U/T

5'-dCpdApdCpdGpdCpdApdTpdApdGpdCpdGpdCpdCpdCpdCpdApdApdCpdCpdCpdCpdApdGpdTpdCpdGpdApdTpdGpdApdApdApdTpdTpdGpdCpdGpdTpdCpdGpdCpdGpdGpdGpdTpdGpdCpdCpdTpdApdTpdGpdCpdGpdTpdGp-3'

Molecular Weight: 17187.1 g/mole

Extinction Coefficient: 519700

Binding Conditions / Buffer

Dulbecco’s phosphate buffered saline solution (DPBS). It contains 138 mM NaCl, 2.67 mM KCl, 8.1 mM Na2HPO4, 1.47 mM KH2PO4, 1 mM CaCl2, and 0.5 mM MgCl2

Binding Temp: 25 °C °C

Refolding Protocol

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Wang, Q., Li, Y., Yao, L., Li, H., Zhang, L., Wang, Y., Li, J., Chen, T., Chai, K., Gao, J., Gao, J., Su, L., & Li, X. (2025). High-affinity ssDNA aptamer and chemiluminescent aptasensor for TIMP-1 detection in human serum. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 41(2), 119–126. https://doi.org/10.1007/s44211-024-00673-w

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