Aptamer 3-83 Aptamer Details
ID# 8246
Structure
Chemistry
DNA
Target
Uridine 5' diphosphate
Category
Other
Affinity (Kd)
274.8 µM
Length
40
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-dApdGpdGpdGpdCpdTpdApdTpdGpdApdGpdCpdCpdCpdTpdGpdCpdGpdCpdCpdGpdApdCpdGpdTpdCpdApdGpdGpdCpdGpdCpdApdCpdCpdGpdApdGpdApdCp-3'
Molecular Weight: 13200
Extinction Coefficient:
Binding Conditions / Buffer
B&W Buffer (5mM Tris-HCl, 0.5 mM EDTA, 1 M NaCl, pH 7.5
Binding Temp: 21°C
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Guo, S., Lin, J., Lin, L. et al. Selecting small molecule DNA aptamers with significant conformational changes for constructing transcriptional switches and biosensors. Sci. China Chem. 66, 1529–1536 (2023). https://doi.org/10.1007/s11426-022-1540-y
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