Apta 5 Aptamer Details
ID# 8124
Structure
Chemistry
DNA
Target
Carcinoembryonic antigen (CEA)
Category
Protein
Affinity (Kd)
37.8 nM
Length
74
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5’-dTpdCpdGpdCpdGpdCpdGpdApdGpdTpdCpdGpdTpdCpdTpdGpdGpdGpdApdGpdCpdTpdApdCpdGpdTpdTpdTpdApdGpdCpdGpdApdGpdTpdCpdCpdGpdApdCpdGpdCpdTpdCpdGpdGpdTpdGpdCpdCpdTpdCpdTpdTpdCpdCpdCpdGpdCpdApdTpdCpdGpdTpdCpdCpdTpdCpdCpdCp-3’
Molecular Weight: 21404.8
Extinction Coefficient: 621800
Binding Conditions / Buffer
Not given.
Binding Temp: 37°C
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Melo, M.; Correa, C.; Cunha, P.; Goes, A.; Gomes, D.; Andrade, A. DNA aptamers selection for carcinoembryonic antigen (CEA). Bioorg. Med. Chem. Lett. 2020 May 23; 30(15): 127278. DOI: 10.1016/j.bmcl.2020.127278
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