Apt51 Aptamer Details
ID# 9093
Structure
Chemistry
DNA
Target
interleukin-2 receptor-α
Category
Small Organic
Affinity (Kd)
13.4 nM
Length
80
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
dGpdCpdTpdGpdTpdGpdTpdGpdApdCpdTpdCpdCpdTpdGpdCpdApdApdApdTpdApdTpdApdGpdCpdGpdGpdGpdCpdApdGpdGpdGpdGpdTpdGpdGpdGpdGpdGpdGpdGpdTpdGpdTpdTpdTpdGpdCpdGpdGpdCpdTpdCpdTpdGpdGpdGpdApdTpdCpdGpdCpdApdGpdCpdTpdGpdTpdApdTpdCpdTpdTpdGpdTpdCpdTpdCpdCp
Molecular Weight: 24884 g/mole
Extinction Coefficient: 743200
Binding Conditions / Buffer
5 ml binding buffer (50 mM K2HPO4 pH 7.5, 150 mM NaCl, 0.05% Tween-20, BSA 1 μg/ml, 0.1 mg/ml yeast tRNA
Binding Temp: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Shahdordizadeh M, Taghdisi SM, Sankian M, Ramezani M, Abnous K. Design, isolation and evaluation of the binding efficiency of a DNA aptamer against interleukin 2 receptor alpha, in vitro. Int Immunopharmacol. 2017 Dec;53:96-104. doi: 10.1016/j.intimp.2017.10.011. Epub 2017 Oct 18. PMID: 29055191.
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