Aptagen

Apt-E1(Erythromycin-Resistant Methyltransferase (Erm) Aptamer Details

ID# 9927
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Structure
Apt-E1(Erythromycin-Resistant Methyltransferase (Erm) structure
Chemistry
DNA
Target
Erythromycin-Resistant Methyltransferase (Erm 42)
Category
Small Organic
Affinity (Kd)
7.8 nM
Length
73
Aptazyme
No

Sequence (3-char table code)

G A C U/T
5'-dCpdGpdApdApdApdTpdGpdApdTpdGpdGpdCpdTpdApdTpdTpdTpdCpdCpdApdCpdGpdCpdApdCpdCpdGpdGpdTpdApdApdApdApdGpdGpdGpdTpdTpdGpdTpdTpdGpdTpdTpdGpdTpdTpdGpdGpdTpdApdCpdTpdGpdGpdGpdTpdCpdApdGpdCpdTpdGpdApdTpdCpdCpdTpdGpdApdTpdGpdGp-3'
Molecular Weight: 22659.7 g/mole
Extinction Coefficient: 698600

Binding Conditions / Buffer

79.1°C
Binding Temp: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Refolding Protocol

If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Leena Laxmikant Badgujar, Damini Sahu, Ruchi Anand, and P. I. Pradeepkumar ACS Infectious Diseases 2026 12 (1), 212-223 DOI: 10.1021/acsinfecdis.5c00756
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