ApoE 06 Aptamer Details
ID# 7963
Structure
Chemistry
DNA
Target
Apolipoprotein E
Category
Protein
Affinity (Kd)
938 pM
Length
59
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-dGpdApdTpdApdApdApdCpdGpdCpdCpdTpdTpdGpdApdTpdTpdApdApdApdGpdGpdCpdCpdCpdApdGpdTpdTpdCpdTpdTpdTpdApdGpdGpdCpdCpdTpdApdCpdApdCpdGpdTpdGpdCpdTpdGpdCpdGpdApdCpdApdTpdTpdApdApdTpdTp-3'
Molecular Weight: 18119.84
Extinction Coefficient: 563700
Binding Conditions / Buffer
PBSMCT (DPBS with 2.5 mM MgCl2, 1 mM CaCl2, 0.05% TWEEN-20)
Binding Temp: 23°C
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Wang, J., Gong, Q., Maheshwari, N., Eisenstein, M., Luz Arcila, M., Kosik, K., & Soh, T. Particle Display: A Quantitative Screening Method for Generating High-Affinity Aptamers. Angew. Chem. Int. Ed. 2014, 53, 4796ƒ??4801
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