Aptagen

Anti Glioblastoma Cells (GBM128) Aptamer Details

ID# 7873
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Structure
Anti Glioblastoma Cells (GBM128) structure
Chemistry
DNA
Target
Glioblastoma Cell
Category
Cells
Affinity (Kd)
20 nM
Length
83
Aptazyme
No

Sequence (3-char table code)

G A C U/T
5'dGpdApdApdTpdTpdCpdApdGpdTpdCpdGpdGpdApdCpdApdGpdCpdGpdApdCpdGpdGpdTpdGpdGpdGpdApdGpdCpdCpdCpdCpdApdApdApdTpdApdApdTpdTpdCpdTpdTpdGpdCpdGpdApdTpdTpdApdTpdTpdApdGpdTpdGpdTpdApdApdGpdCpdGpdGpdApdTpdGpdGpdApdCpdGpdApdApdTpdApdTpdCpdGpdTpdCpdTpdCpdCpdCp-3'
Molecular Weight: 25689.73
Extinction Coefficient: 812600

Binding Conditions / Buffer

25 µM glucose 4 µM yeast tRNA 15 µM BSA 5 mM MgCl2 in PBS (pH = 7.4) 1 hour incubation with cells
Binding Temp: 4°C

Refolding Protocol

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Kang et al. Selection of DNA Aptamers against Glioblastoma Cells with High Affinity and Specificity (PLOSone)
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