Anionic Porphyrins (ST1) Aptamer Details
ID# 7849
Structure
Chemistry
DNA
Target
N-methylmesoporphyrin IX (NMM), mesoporphyrin IX (MPIX), and other metalloderivatives
Category
Small Organic
Affinity (Kd)
0.7 µM
Length
25
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-dApdApdCpdGpdTpdGpdGpdGpdApdGpdGpdGpdCpdGpdGpdTpdGpdGpdTpdGpdTpdTpdGpdApdAp-3'
Molecular Weight: 7883.18
Extinction Coefficient: 253400
Binding Conditions / Buffer
SB Buffer: 100 mM Tris-acetate (pH 7.4), 200 mM sodium acetate, 25 mM potassium acetate, 10 mM magnesium acetate, 0.5% Triton X-100, and 5% dimethyl sulfoxide.
Binding Temp: RT°C
Refolding Protocol
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Y Li, CR Geyer, and D Sen. (1996) Recognition of anionic porphyrins by DNA aptamers. Biochem. 35:6911-6922.
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