Angiogenic endothelial cells Aptamer Details
ID# 7632
Structure
Chemistry
Peptide
Target
Aminopeptidase N
Category
Tissue
Affinity (Kd)
N/A nM
Length
3
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
NH2-AsnGlyArg-COOH
Molecular Weight: 319.43
Extinction Coefficient:
Binding Conditions / Buffer
Wash buffer in cellular association assays: PBS.
Peptides were also delivered in vivo to mice.
Binding Temp:
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Pastorino et al. "Vascular Damage and Anti-angiogenic Effects of Tumor Vessel-Targeted Liposomal Chemotherapy." Cancer Research, 63(2003): 7400-7409.
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