Ancrod-55 Aptamer Details
ID# 8224
Structure
Chemistry
DNA
Target
ancrod
Category
Protein
Affinity (Kd)
3.0 nM
Length
40
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-dGpdGpdApdCpdCpdGpdApdCpdCpdCpdTpdTpdTpdApdGpdCpdApdTpdTpdTpdApdTpdGpdApdCpdCpdCpdTpdTpdGpdTpdCpdApdTpdCpdGpdGpdGpdCpdTp-3'
Molecular Weight: 12292.93
Extinction Coefficient:
Binding Conditions / Buffer
50 mM Tris-HCl, pH 7.5
150 mM NaCl
2 mM MgCl2
Binding Temp: 23°C
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Alomran, N, Raja, C, Alsolaiss, J, Casewell, NR, Zourob, M. (2022) Exploring the utility of ssDNA aptamers directed against snake venom toxins as new therapeutics for snakebite envenoming. Toxins, 14, 469. https://doi.org/10.3390/toxins14070469.
Request a Quote
Have your aptamer oligo synthesized by Aptagen.
