AMB2F Aptamer Details

ID# 8827

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Structure

Chemistry

DNA

Target

Indazole-3-carboxamidesynthetic cannabinoids

Sequence (3-char table code)

G A C U/T

5'-dGpdGpdGpdApdCpdGpdApdCpdTpdApdGpdCpdGpdGpdTpdGpdTpdTpdGpdGpdTpdCpdGpdGpdApdGpdTpdGpdGpdTpdGpdGpdApdApdTpdCpdTpdApdGpdTpdCpdGpdTpdCpdCpdCp-3'

Molecular Weight: 14334.3

Extinction Coefficient: 443500

Binding Conditions / Buffer

10 mM Tris, pH 7.4, 137mM NaCl, 2.7 mM KCl, 1 mM MgCl2, 5% DMSO

Binding Temp: 23°C

Refolding Protocol

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Canoura J., Nguyen, T., Byrd C., Hill R., Liu Y., & Xiao L. (2024). Generation of High-Affinity Aptamers for Indazole Synthetic Cannabinoids. Analytical Chemistry, 96, 11488-11497. https://doi.org/10.1021/acs.analchem.4c02151

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