ADCC Bi-specific Aptamer (bsA17) Aptamer Details
ID# 7861
Structure
Chemistry
DNA
Target
CD16a positive cell lines
Category
Protein
Affinity (Kd)
N/A nM
Length
132
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-dCpdCpdApdCpdTpdGpdCpdGpdGpdGpdGpdGpdTpdCpdTpdApdTpdApdCpdGpdTpdGpdApdGpdGpdApdApdGpdApdApdGpdTpdGpdGpdGpdCpdApdGpdGpdTpdCpdGpdCpdApdGpdGpdTpdCpdGpdGpdApdGpdGpdGpdApdApdApdApdGpdTpdTpdApdTpdCpdApdGpdGpdCpdTpdGpdGpdApdTpdGpdGpdTpdApdGpdCpdTpdCpdGpdGpdTpdCpdGpdGpdGpdGpdTpdGpdGpdGpdTpdGpdGpdGpdTpdTpdGpdGpdCpdApdApdGpdTpdCpdTpdGpdApdTpdTpdApdGpdTpdTpdTpdTpdGpdGpdApdGpdTpdApdCpdTpdCpdGpdCpdTpdCpdCp-3'
Molecular Weight: 41337.79
Extinction Coefficient: 1284900
Binding Conditions / Buffer
Binding Buffer: DPBS with 0.05% BSA
Binding Temp: 37°C
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Boltz A, Plater B, Hock B, et al. (2011) Bi-specific Aptamers Mediating Tumour Cell Lysis. J Biol Chem. 286: 21896-21905.
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