ACG03 Aptamer Details
ID# 7892
Structure
Chemistry
DNA
Target
gastric cancer cell-line HGC-27
Category
Cells
Affinity (Kd)
16.49 nM
Length
78
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-dApdCpdGpdCpdTpdCpdGpdGpdApdTpdGpdCpdCpdApdCpdTpdApdCpdApdGpdGpdGpdGpdGpdGpdTpdGpdGpdTpdCpdCpdTpdGpdApdGpdGpdGpdTpdGpdGpdTpdGpdTpdGpdGpdTpdTpdGpdGpdTpdTpdTpdGpdGpdTpdTpdTpdCpdCpdTpdCpdApdTpdGpdGpdApdCpdGpdTpdGpdCpdTpdGpdGpdTpdGpdApdCp-3'
Molecular Weight: 24321.75
Extinction Coefficient: 730600
Binding Conditions / Buffer
4.5 g/l glucose, 5 mM MgCl2,2 mg/ml BSA and 0.2 mg/ml yeast tRNA dissolved in PBS buffer
Binding Temp: 4°C
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Zhang, X. et al. "A cell-based single-stranded DNA aptamer specifically targets gastric cancer." The International Journal of Biochemistry & Cell Biology 2014, 46: 1-8.
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