Aptagen

A23P3 Aptamer against IL-23 (P19 subunit) Aptamer Details

ID# 9182
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Structure
A23P3 Aptamer against IL-23 (P19 subunit) structure
Chemistry
DNA
Target
IL-23 (P19 subunit)
Category
Protein
Affinity (Kd)
1.37 nM
Length
34
Aptazyme
No

Sequence (3-char table code)

G A C U/T
5'-dGpdGpdTpdGpdGpdTpdApdGpdTpdTpdGpdGpdGpdApdGpdGpdGpdTpdApdGpdGpdGpdTpdGpdGpdTpdGpdGpdTpdApdGpdTpdTpdGp-3'
Molecular Weight: 10817 g/mole
Extinction Coefficient: 344400

Binding Conditions / Buffer

Binding Buffer: 50 mM phosphate, 150 mM NaCl, pH 7.8
Binding Temp: 37°C°C

Refolding Protocol

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference

Rezaee, M. A., Shobeiri, S. S., Moghadam, M., Mashayekhi, K., & Sankian, M. (2024). In vitro identification of single-stranded DNA aptamers targeting human IL-23 using the protein-SELEX strategy. Journal of pharmaceutical and biomedical analysis, 247, 116245. https://doi.org/10.1016/j.jpba.2024.116245
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