A2 Aptamer Details
ID# 8862
Structure
Chemistry
DNA
Target
Murine prion protein (90–231)
Category
Protein
Affinity (Kd)
1.93 µM
Length
72
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-dGpdGpdGpdApdGpdApdCpdApdApdGpdApdApdTpdApdApdApdCpdGpdCpdTpdCpdApdApdTpdGpdGpdTpdGpdGpdTpdApdApdCpdApdGpdApdCpdCpdCpdTpdTpdCpdCpdApdCpdGpdGpdCpdTpdTpdCpdGpdApdCpdApdGpdGpdApdGpdGpdCpdTpdCpdApdCpdApdApdCpdApdGpdGpdCp-3'
Molecular Weight: 22262.5
Extinction Coefficient: 709900
Binding Conditions / Buffer
5 mM Tris buffer (pH 7.4)
Binding Temp: 23°C
Refolding Protocol
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Matos C.O., Passos Y.M., Amaral M.J., Macedo B., Tempone M.H., et al. (2020). Liquid-liquid phase separation and fibrillation of the prion protein modulated by a high-affinity DNA aptamer. The FASEB Journal, (34)1, 365-385. https://doi.org/10.1096/fj.201901897r
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