A15 Aptamer Details
ID# 7919
Structure
Chemistry
RNA
Target
Penetrating the Blood Brain Barrier (BBB)
Category
Other
Affinity (Kd)
. nM
Length
54
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
rGprGprGp rAprGprGp rAprCprGp rApUrGp rCprGprGp rCprGpU rApUU rGprCprGp rCprGprAp rGprGprAp UUrAp UrCprCp rGprCpU rCprApU rCprGpU UrGpU UrGpU UrGpU rGprCprAp rGprAprCp rGprAprCp UrCprGp rCprCprCp rGprAp
Molecular Weight: 17706.87
Extinction Coefficient: 523600
Binding Conditions / Buffer
10mM HEPES, pH 7.4, 50mM NaCl, 1mM MgCl2, 1mM CaCl2, 0.01% BSA
Binding Temp: 37°C
Refolding Protocol
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Congsheng Cheng, Yong Hong Chen, Kim A Lennox, Mark A Behlke, Beverly L Davidson, "In vivo SELEX for Identification of Brain-penetrating Aptamers" Molecular Therapy-Nucleic Acids (2013)2, e67, American Society of Gene & Cell Therapy
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