1R6 (αSyn1-95) Aptamer Details
ID# 10145
Structure
Chemistry
RNA
Target
αSyn1-95 (N-terminal 95-residue fragment of αSyn)
Category
Protein
Affinity (Kd)
11 nM
Length
29
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-rCprGprAprUprCprGprCprAprGprUprCprAprCprGprUprGprCprGprGprUprUprUprGprUprGprUprCprGprCprGp-3'
Molecular Weight: 8803.6 g/mole
Extinction Coefficient: 253100
Binding Conditions / Buffer
BLI assay with PBS incubation (8.1 mM Na2HPO4, 1.5 mM KH2PO4, 2.7 mM KCl, 14 mM NaCl, pH 7.4)
Binding Temp: 30°C
Refolding Protocol
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Murakami, K., Van Nguyen, T.H., Tsuda, L. et al. Development of an RNA aptamer as a therapeutic agent for synucleinopathies. Nat Commun 17, 7118 (2026). https://doi.org/10.1038/s41467-026-75209-z
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