17OAp1-24mm Aptamer Details
ID# 9549
Structure
Chemistry
DNA
Target
Hamster PrPSc
Category
Protein
Affinity (Kd)
10 mmol/L CAPS, 120 mmol/L
KSCN, 3.0 mmol/L NaN3, 2% Triton X-100, 1 PBS, pH
7.6 used as the washing buffer
Length
36
Aptazyme
No
Sequence (3-char table code)
G
A
C
U/T
5'-dCpdTpdTpdApdTpdGpdTpdCpdCpdGpdTpdGpdCpdCpdApdApdApdCpdGpdGpdApdCpdGpdGpdGpdGpdGpdGpdApdCpdApdApdTpdApdGp-3'
Molecular Weight: 11175.3 g/mole
Extinction Coefficient: 353600
Binding Conditions / Buffer
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Binding Temp:
Refolding Protocol
If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Reference
Wang P, Hatcher KL, Bartz JC, Chen SG, Skinner P, Richt J, Liu H, Sreevatsan S. Selection and characterization of DNA aptamers against PrP(Sc). Exp Biol Med (Maywood). 2011 Apr 1;236(4):466-76. doi: 10.1258/ebm.2011.010323.
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